Publications

2023

Novel 5-aminopyrazoles endowed with anti-angiogenetic properties: Design, synthesis and biological evaluation. 

Matteo Lusardi, Bernhard Wehrle-Haller, Adama Sidibé, Marco Ponassi, Erika Iervasi, Camillo Rosano, Chiara Brullo and Andrea Spallarossa. 

European Journal of Medicinal Chemistry 260, 115727. doi: 10.1016/j.ejmech.2023.115727 , 

2021

Synthesis, functional proteomics and biological evaluation of new 5-pyrazolyl ureas as potential anti-angiogenic compounds. 

Elva Morretta, Adama Sidibé, Andrea Spallarossa, Antonello Petrella, Elda Meta, Olga Bruno, Maria Chiara Monti, Chiara Brullo. 

European Journal of Medicinal Chemistry 226, 113872, 2021, 

New Series of Pyrazoles and Imidazo-Pyrazoles Targeting Different Cancer and Inflammation Pathways. 

Maria Grazia Signorello, Federica Rapetti, Elda Meta, Adama Sidibé, Olga Bruno, Chiara Brullo.  

Molecules 26 (19), 5735, 2021

2020

Induced pluripotent stem cells to understand mucopolysaccharidosis. i: demonstration of a migration defect in neural precursors. 

Silvin Lito, Adama Sidibé, Sten Ilmjarv, Patricie Burda, Matthias Baumgartner, Bernhard Wehrle-Haller, Karl-Heinz Krause, Antoine Marteyn 

Cells 9 (12), 2593, 2020

Study of Human Pro-Angiogenic Monocytes from Blood of Diabetic patients including Those with Ischemic Diabetic Foot Ulcers. 

Ilker Uçkay, Benjamin Kressmann, Beat A. Imhof, Daniel Lew, Benjamin A. Lipsky and Adama Sidibé.

Stem Cells and Development 29 (14), 911-918, 2020

2019 

Impaired reverse transendothelial migration capacity governs the enhanced abluminal accumulation of diabetic CD14+ monocytes. 

D Semo, A Sidibé, SK Shanmuganathan, N Mueller, UA Mueller, FD Boehmer, B Imhof, R Godfrey, J Waltenberger 

EUROPEAN HEART JOURNAL 40, 1946-194629 (14), 911-918, 2019

2018

Simultaneous study of the recruitment of monocyte subpopulations under flow in vitro. 

Patrcia Ropraz, Beat A Imhof, Thomas Matthes, Bernhard Wehrle-Haller and Adama Sidibé 

Journal of Visualized Experiments (JoVE), (141), e58509, doi:10.3791/58509, 2018

Angiogenic factors-driven Inflammation promotes the extravasation of human proangiogenic monocytes to tumours. 

Adama Sidibé, Patricia Ropraz, Stéphane Jemelin, Yalin Emre, Marine Poittevin, Marc Pocard, Paul F. Bradfield and Beat A. Imhof.

Nature Communications, 9, 355; doi:10.1038/s41467-017-02610-0, 2018

The tyrosine-kinase inhibitor sunitinib targets vascular endothelial (VE)-cadherin: a marker of response to antitumoural treatment in metastatic renal cell carcinoma. 

Helena Polena, Julie Creuzet, Maeva Dufies, Adama Sidibé, Abir Khalil-Mgharbel, Aude Salomon, Alban Deroux, Jean-Louis Quesada, Caroline Roelants, Odile Filhol, Claude Cochet, Ellen Blanc, Céline Ferlay-Segura, Delphine Borchiellini, Jean-Marc Ferrero, Bernard Escudier, Sylvie Négrier, Gilles Pages and Isabelle Vilgrain 

British Journal of Cancer. 2018 Mar 22. doi: 10.1038/s41416-018-0054-5, 2018

2017

The pyrazolyl-urea GeGe3 inhibits angiogenesis by targeting dystrophia myotonica protein kinase (DMPK)1. 

Elda Meta, Beat A. Imhof, Patricia Ropraz, Richard J. Fish, Chiara Brullo, Olga Bruno and Adama Sidibé

Oncotarget Nov 21;8(64):108195-108212. doi: 10.18632/oncotarget.22598, 2017 

Design, synthesis and biological evaluation of new pyrazolyl-ureas and imidazopyrazolecarboxamides able to interfere with MAPK and PI3K upstream signaling involved in angiogenesis. 

Elda Meta, Chiara Brullo, Adama Sidibé, Beat A. Imhof and Olga Bruno 

European Journal of Medicinal Chemistry, 133, 24-35 DOI: 10.1016/j.ejmech.2017.03.066, 2017 

2015

5'-Ectonucleotidase/CD73 expression on lymph-circulating lymphocytes and lymphatic endothelial cells offers new paths to explore barrier function. 

Adama Sidibé and Beat A. Imhof

European Journal of Immunology. 2015 Feb;45(2):371-5.

2014

VE-cadherin phosphorylation decides: vascular permeability or diapedesis. 

Adama Sidibé and Beat A. Imhof

Nature Immunology. 2014 Mar;15(3):215-7.

Soluble Vascular Endothelial (VE)-Cadherin: Toward a Marker of Endothelial Dysfunction. In book: Molecular Mechanisms of Angiogenesis 

Adama Sidibé, Helena Polena, Tiphaine Mannic, Barry Stidder, Laurence Bouillet and Isabelle Vilgrain

From Ontogenesis to Oncogenesis, Chapter: 23, pp.461-478 DOI: 10.1007/978-2-8178-0466-8, 

Springer Paris,

Endothelial junctions: exploiting their instability in the development of biomarkers for vascular remodeling. 

Laurence Bouillet, Adama Sidibé, Helena Polena, Tiphaine Mannic, Alban Deroux, Barry Stidder, Olivier Vittecoq et Isabelle Vilgrain 

Medecine/ Science (Paris). 2014 Jun-Jul;30(6-7):633-5, DOI: 10.1051/medsci/20143006012 

VE-cadherin Y685F knock-in mouse is sensitive to vascular permeability in recurrent angiogenic organs. 

Adama Sidibé, Helena Polena, Karin Pernet-Gallay, Jeremy Razanajatovo, Tiphaine Mannic, Nicolas Chaumontel, Soumalamaya Bama, Irène Maréchal, Philippe Huber, Danielle Gulino-Debrac, Laurence Bouillet and Isabelle Vilgrain 

American Journal Physiology- Heart and Circulatory physiology. 2014 Aug 1;307(3):H455-63. 

Dynamic phosphorylation of VE-cadherin Y685 throughout mouse estrous cycle in ovary and uterus. 

Adama Sidibé, Helena Polena, Jeremy Razanajatovo, Tiphaine Mannic, Nicolas Chaumontel, Soumalamaya Bama, Irène Maréchal, Philippe Huber, Danielle Gulino-Debrac, Laurence Bouillet and Isabelle Vilgrain

American Journal Physiology- Heart and Circulatory physiology. 2014 Aug 1;307(3):H448-54.

2013

Evidence for post-translational processing of vascular endothelial (VE)-cadherin in brain tumors: towards a candidate biomarker. 

Isabelle Vilgrain, Adama Sidibé, Helena Polena, Francine Cand, Tiphaine Mannic, Mélanie Arboleas, Sandra Boccard, Antoine Baudet, Danielle Gulino-Debrac, Laurence Bouillet, Jean-Louis Quesada, Christophe Mendoza, Jean-François Lebas, Laurent Pelletier and François Berger

PLoS One. 2013 Dec 16;8(12):e80056. doi:10.1371/journal.pone.0080056. eCollection 2013

Auto-antibodies to vascular endothelial cadherin in humans: association with autoimmune diseases.

Laurrence Bouillet, Antoine E Baudet, Alban Deroux, Adama Sidibé, Chantal Dumestre-Perard, Tiphaine Mannic, Bertrand Treillard, Melanie A Arboleas, Christophe A Chiquet, Danielle Gulino-Debrac and Isabelle Y Vilgrain

Laboratory Investigation. 2013 Nov;93(11):1194-202

2012

Soluble VE-cadherin in rheumatoid arthritis patients correlates with disease activity: Evidence for TNFα-induced VE-cadherin cleavage. 

Adama Sidibé, Tiphaine Mannic, Mélanie Arboleas, Mariela Subileau, Danielle Gulino‐Debrac, Laurence Bouillet, Mary Jan, Thibault Vandhuick, Xavier Le Loët, Olivier Vittecoq and Isabelle Vilgrain

Arthritis & Rheumatism 64(1): 77-87

Un nouveau marqueur d’activité de la polyarthrite rhumatoïde : la VE-cadhérine circulante. 

Laurence Bouillet, Adama Sidibé, Tiphaine Mannic, Mariela Subileau, Danielle Gulino‐Debrac, Olivier Vittecoq and Isabelle Vilgrain

La Revue de Médecine Interne, 2012, 33: S53

Reply to "Vascular endothelial cadherin: A possible link between endocytosis and ectodomain shedding", 

Laurence Bouillet, Adama Sidibé and Isabelle Vilgrain

Journal of Allergy and Clinical Immunology, 129(1): 266-267